From Memios
The Longevity Letter
Practical writing and video on living strong and active into your 90s. No hype, no supplements to sell. Just what the evidence supports and what it looks like on an ordinary Tuesday.
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SupplementsCopper
Copper is essential, and deficiency causes anaemia, low white cells and nerve damage that copper can correct.
2026-09-29 · 8 min read
SupplementsCordyceps
Limited evidence. Evidence is limited and inconsistent.
2026-09-29 · 10 min read
SupplementsDHEA
Disputed. The evidence is mixed and mostly disappointing.
2026-09-29 · 17 min read
SupplementsDigestive enzyme blends
For people whose pancreas does not make enough enzymes (exocrine pancreatic insufficiency, for example in cystic fibrosis), prescription enzyme replacement is the standard treatment.
2026-09-29 · 7 min read
SupplementsDPP IV protease and gluten-degrading enzyme supplements
Common DPP-IV-type digestive enzyme supplements do not protect people with coeliac disease: laboratory testing found they leave the immune-triggering parts of gluten largely intact.
2026-09-29 · 11 min read
SupplementsEchinacea
Disputed. The evidence is disputed rather than settled.
2026-09-29 · 13 min read
SupplementsElderberry
The honest summary is that the evidence is thin and uncertain rather than settled either way.
2026-09-29 · 14 min read
SupplementsEleuthero
Not supported by the research. It is sold as an 'adaptogen' for stress, fatigue and stamina.
2026-09-29 · 10 min read
SupplementsEvening primrose oil
Not supported by the research. For the two uses with the most trial data, the answer is that it does not work.
2026-09-29 · 15 min read
SupplementsExogenous ketones
Limited evidence. The evidence is limited and mixed.
2026-09-29 · 13 min read
SupplementsFenugreek
Fenugreek seed is promoted mainly for blood sugar, for cholesterol and as a galactagogue to increase breast milk.
2026-09-29 · 16 min read
SupplementsFeverfew
Limited evidence. The evidence is thin and Cochrane rates it low quality.
2026-09-29 · 25 min read
SupplementsFlaxseed and flaxseed oil
The state of the evidence is that whole ground flaxseed has a measurable but modest effect on blood lipids and blood pressure in meta-analyses of randomised trials.
2026-09-29 · 19 min read
SupplementsFolate and folic acid
Folic acid taken around conception has high-quality Cochrane evidence for preventing neural tube defects.
2026-09-29 · 12 min read
SupplementsGarcinia cambogia
Limited evidence. It is sold for weight loss.
2026-09-29 · 15 min read
SupplementsGarlic
Garlic's best-supported effect is a modest reduction in blood pressure in people who already have hypertension: meta-analyses report systolic reductions of roughly 4 to 7 mmHg.
2026-09-29 · 19 min read
SupplementsGelatin
Gelatin is digested into amino acids and small peptides, and blood levels of glycine, proline, hydroxyproline and hydroxylysine rise within an hour of taking it.
2026-09-29 · 12 min read
SupplementsGinger
Ginger is best supported for nausea in pregnancy, where pooled trials show it eases nausea, though it did not significantly reduce vomiting and the evidence is low quality.
2026-09-29 · 9 min read
SupplementsGlucosamine
Disputed. The evidence is disputed rather than settled.
2026-09-29 · 18 min read
SupplementsGlutamine
Limited evidence. Claims for glutamine centre on gut lining, immunity, recovery and muscle.
2026-09-29 · 14 min read
SupplementsGlutathione
Glutathione's role inside cells is not in doubt; what is disputed is whether swallowing it changes anything.
2026-09-29 · 14 min read
SupplementsGoji berry
Limited evidence. Goji is marketed for general well-being, antioxidant status and eye health.
2026-09-29 · 16 min read
SupplementsGoldenseal
What goldenseal has actually been shown to do in people is interfere with drug metabolism, not treat disease.
2026-09-29 · 12 min read
SupplementsGrape seed extract
Limited evidence. Meta-analyses of small trials find a small drop in blood pressure and heart rate.
2026-09-29 · 10 min read